Methylation Support

Methylation Support provides a combination of B vitamins, choline, and betaine to help support homocysteine level.

  • Dairy Free
  • Gluten Free
  • Soy Free
  • Vegan


Medicinal Ingredients per Capsule:
Vitamin B6 (pyridoxal 5-phosphate) 167 mg
Folate (calcium L-5-methyltetrahydrofolate, Metafolin®* 133 mcg
Vitamin B 12(methylcobalamin) 267 mcg
Betaine (from Beta vulgaris root) 500 mg
Choline (choline bita 25 mg

Non-Medicinal Ingredients: Hypromellose, cellulose, silica.

Adult Dose: Take one capsule three times daily or as recommended by your healthcare practitioner

If you are pregnant or breastfeeding; or if you have high cholesterol, consult your healthcare practitioner


Vegetarian-friendly vitamin B complex

  • Helps the body to metabolize carbohydrates, fats and proteins
  • Helps in red blood cell and tissue formation
  • Provides 50 mg of vitamin B6, 801 mcg of vitamin B12 and 400 mcg of folate (from Metafolin®) per day
  • Helps to prevent vitamin B6, vitamin B12, and folate deficiency

Methylation Support provides a combination of B vitamins, choline, and betaine to help support homocysteine level.1

Homocysteine is an amino acid that can be further metabolized into methionine or cysteine.1

Normal homocysteine levels are necessary for the methylation of nucleic acids, proteins and lipids, as well as protein production.1

A randomized, double-blind trial involving 76 adults demonstrated that supplementation with 1.5 g of betaine daily for six weeks significantly better maintained homocysteine levels when compared to a placebo treatment.2

Betaine also helps support liver function through its role in stimulating the production and export of very low density lipoproteins (VLDL) from the liver.3

Methylation Support contains the physiologically active forms of vitamin B6, folate and vitamin B12, B vitamins involved in tissue formation, red blood cell formation, and macronutrient metabolism, respectively.4 As a result of their interrelated pathways, it is important to have metabolic balances between choline, betaine, homocysteine, vitamin B6, vitamin B12 and folate.5


1. Selhub, J. Food and Nutrition Bulletin. 2008; 29(2 Suppl): S116-S125.
2. Olthof, MR, van Vliet, T, Boelsma, E, Verhoef, P.
J. Nutr. 2003; 133: 4135-4138.
3. Craig, SAS. Am J Clin Nutr. 2004; 80: 539-549.
4. Combs, GF. (2012). The Vitamins (4th ed.). USA: Elsevier.
5. Michel, V, Yuan, Z, Ramsubir, S, Bakovic, M. Exp Biol Med. 2006; 231: 490-504.

Additional information

Weight 0.105 kg


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